Tab Mix Plus

There's a custom button available now - it will toggle TMP' focus option left/right after closing a tab. Thanks rawny!
Of course, you need the Custom Buttons² ext., but with hundreds and hundreds of buttons available already (some of which are made specifically to work with TMP and some can replace other extensions) and a very helpful forum (with wiki and video tutorials), i don't think you'll regret.
Good Luck!

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VistaHP/Fx latest beta/TMP latest dev.build/Troubleshooting TMP/My styles

Yes, this is really a wonderful CB button that you'll never regret to use it if you use TMP simultaneously.

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FF latest ver, TMP latest ver, Vista

Just thought I'd update this to say that I've released 3 new custom buttons which can be found here: http://custombuttons2.com/forum/post3736.html#p3736
These each provide access to a menu which allows you to set the TMP on-tab-close focus behaviour (as opposed to the original button which simply toggled between left and right tab focusing).

As makondo said in his post, you will need the Custom Buttons² extension to install any of these buttons, but it is well worth it as there are many many buttons available besides the four mentioned here

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Rawny ~ Custom Buttons² ~ Custom buttons being used by me